1925–1928
The construction of the new Clemmons School began in 1925 and was opened later in the Fall of the year. Clemmons School’s first basketball team formed in 1925–26, playing on outdoor courts. By 1927–28, the first baseball team was established, and a lunchroom was built.

1930s
The school’s culture flourished with class plays, Halloween carnivals, and the creation of clubs such as the Key Club, Keyettes, FFA, and FHA. In 1931–32, Theodore Rondthaler became principal, founding a student orchestra with his wife, Alice. In 1932, he introduced the Christmas Pageant, a cherished tradition lasting until 1961. The orchestra went on to win six consecutive Class C State Championships (1932–1937). Around 1933, two clay tennis courts were built where the Broyhill Annex (Old Public Library) is located today. The sports program grew to include track, soccer, and tennis. By 1936, the girls’ track team had captured the county championship, and in 1938, the first cheerleading squad was formed.

1940s
A WPA-built gymnasium was completed in 1940, its basement serving as a community cannery during WWII. The school newspaper, The Chatterbox, began publication. Clemmons fielded its first (and only) 11-man football team in 1941; however, WWII prevented them from having a team during the subsequent war years. In 1944, the baseball team won the Class C Western State Championship. In 1945, the state mandated the addition of a 12th grade, and T. Ray Gibbs became principal. Clemmons was reclassified to Class B in 1946, as Class C was eliminated.

1947–1950
Clemmons launched its first six-man football team in 1947–48, and the baseball team captured the Class B State Championship. That same year marked the first issue of the Clemmemories yearbook, which continued until 1956. The 1948–49 school year brought more success: the football team won the Six-Man Class B State Championship, while the baseball team earned a second consecutive Class B state title. In 1949, a cafeteria, four classrooms, and a shop/agriculture building were added. A new athletic complex—with a football field, baseball diamond, grandstand, and lights—was built for $30,000, making it the second lighted stadium in Forsyth County. In 1949-1950, the Clemmons football team was the Six-Man Class B State Runner-up, the basketball team won the Forsyth County title, and the baseball team claimed its third straight Class B State Championship.